Search results for "Biomechanical strength"

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Constitutive modeling of ascending thoracic aortic aneurysms using microstructural parameters.

2016

Ascending thoracic aortic aneurysm (ATAA) has been associated with diminished biomechanical strength and disruption in the collagen fiber microarchitecture. Additionally, the congenital bicuspid aortic valve (BAV) leads to a distinct extracellular matrix structure that may be related to ATAA development at an earlier age than degenerative aneurysms arising in patients with the morphological normal tricuspid aortic valve (TAV). The purpose of this study was to model the fiber-reinforced mechanical response of ATAA specimens from patients with either BAV or TAV. This was achieved by combining image-analysis derived parameters of collagen fiber dispersion and alignment with tensile testing dat…

Aortic valvemedicine.medical_specialtyMaterials scienceBicuspid aortic valve0206 medical engineeringFinite Element AnalysisBiomedical EngineeringBiophysics02 engineering and technology030204 cardiovascular system & hematologyThoracic aortic aneurysmModels BiologicalArticleExtracellular matrixSettore ING-IND/14 - Progettazione Meccanica E Costruzione Di Macchine03 medical and health sciencesAortic aneurysmFinite Element Analysi0302 clinical medicineBicuspid aortic valveFinite elementmedicine.arteryInternal medicineTensile StrengthAscending aortamedicineHumansAortaMechanical PhenomenaAortaAortic aneurysmAortic Aneurysm ThoracicSettore ING-IND/34 - Bioingegneria IndustrialeBiomechanical strengthExtracellular matrixAnatomymedicine.disease020601 biomedical engineeringBiomechanical Phenomenamedicine.anatomical_structureBiophysicCardiologycardiovascular systemCollagenStress MechanicalAortic failureHumanMedical engineeringphysics
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